Our team of health experts, nutritionists, and doctors tested 22 Glutathione supplements and came up with our top 5 most-recommended products. If you are not familiar with the benefits of glutathione we recommend reading our detailed guide below the top 5 list.
For many people suffering from immune debilitating illnesses, high oxidative stress, or just overall fatigue, glutathione supplementation has become a life-changer. Most people report feeling or seeing results in 1-2 weeks of daily supplementation.
CHOOSING THE RIGHT GLUTATHIONE SUPPLEMENT
Ingestion Form: Pills, Capsules, liquid, liposomal and more. When it comes to Glutathione, the form in which the supplement is ingested is of paramount importance. Research shows that only glutathione in liquid form is properly absorbed by the body through the oral mucosa in the mouth and the liver. Unfortunately, research shows that pills, capsules, and even liposomal glutathione supplements are not absorbed by the body and do not increase internal glutathione levels. That’s why we do not recommend any of those products in our top 5 list.
Ingredient Type/Quantity: This refers to the types of ingredients included in the supplement as well as the quantity or concentration per ingredient. Studies show that adults over 40 years old should ingest at least 400mg of Glutathione per day to see optimal results. We recommend taking supplements that include additional vitamins and minerals in addition to Glutathione. Vitamin C, Zinc, and Selenium bring various health benefits on their own and also attribute to the overall performance of Glutathione.
Manufacturer credentials: This refers to the location and manufacturing standards implemented in the production of the supplement. To ensure quality and safety, we recommend purchasing supplements manufactured in the USA with FDA and GMP certifications.
Flavor: This refers to the taste and experience of liquid glutathione supplements. It may not seem like a relevant category. However, glutathione supplements should be taken daily and some have an extremely unpleasant taste or smell. Therefore, we believe that it would be very difficult to consistently take a supplement that produces disgust for its user. Glutathione in liquid form oxidizes very quickly and just hours after being exposed to air it will begin to smell like sulfur or rotten eggs. This also affects the taste and it may become almost intolerable for some.
Price Value: This refers to the overall value based on all the other characteristics mentioned compared to the price of the supplement. Even though Glutathione supplementation can be a life-changer for some, we believe it should be accessible for almost any budget.
THE BEST GLUTATHIONE SUPPLEMENTS OF 2022
1. GlutaDose Wellness®
The Best Overall Glutathione Supplement of 2022
★★★★★ 4.8 (1,371 Reviews)
GlutaDose Wellness is in a class of its own, proving to excel in all our categories and setting the standard for the best option in the market. It is manufactured in a pharmaceutical-grade facility in the USA using Blow-Fill-Seal tech which minimizes human contact and contamination. Each box contains 30 doses of liquid vials making it extremely easy to take and reducing oxidation to a minimum. And since oxidation is so low the taste is excellent. It is citrus flavored and most of our staff actually loved it.
On top of the excellent user experience, the formula contains 500mg of pure Glutathione. This ingredient in pure form is extremely hard to come by since it has a high cost and is difficult to formulate. It also includes 180mg of vitamin C and 10mg of zinc which aid overall immune support function and free radical reduction.
In terms of quality, user experience, ingredients, and overall value, GlutaDose Wellness is hands down the best glutathione supplement on the market.
500mg Glutathione
180mg Vitamin C
10mg Zinc
$60 $49.99BUY NOW
+ High Concentration 500mg Glutathione per dose
+ Lifetime Warranty
+ Multiple Users Enabled
+ 1+ Year Battery Life
+ Apple/Android Compatible App
+ 16 Unique Body Measurements
2. Core Med Science®
★★★★ 4.4 (1,700 Reviews)
CoreMed Science liposompal glutathione liquid provides a powerful concentration of glutathione in liquid form. This supplement is manufactured in the USA in a GMP certified facility using high-grade Setria® Reduced L-Glutathione imported from Japan.
This supplement is presented in one 4 fl oz bottle which presents the issue of oxidation. That causes an extremely unpleasant taste and a sulfuric smell similar to rotten eggs. Unfortunately, the excellent manufacturing and ingredients are hindered by the fact that taking it is simply an unpleasant experience, and as a result, daily use becomes difficult as it worsens over time.
500mg Glutathione
500mg Liposome Blend
$59.99BUY NOW
+ High Concentration 500mg Glutathione per dose
+ Lifetime Warranty
+ Multiple Users Enabled
+ 1+ Year Battery Life
+ Apple/Android Compatible App
+ 16 Unique Body Measurements
–High oxidizing bottle
3. Seeking Health Optimal Liposomal Glutathione ™
★★★★★ 4.5 (380 Reviews)
SeekingHealth Optimal Liposompal Glutathione liquid provides a powerful concentration of glutathione in liquid form very similar to that of CoreMed. This supplement is manufactured in the USA, contains 500mg of glutathione and is presented in one 4 fl oz bottle which brings about the issue of oxidation.
Unfortunately this product also has an extremely unpleasant taste and a sulfuric smell similar to rotten eggs. Once you open the bottle the smell and taste are bearable, however as time progresses it becomes worse. The benefits of glutathione supplementation come about with daily use over weeks and months. When the intake experience is unpleasant then the chances of staying disciplined over time are hindered.
500mg Glutathione
Phosphatidylcholine comples 400mg
$59.95BUY NOW
+ High Concentration 500mg Glutathione per dose
+ Manufactured in the USA
–High oxidizing bottle
4. Designs for Health Liposomal Glutathione Spray
★★★★ 4.4 (230 Reviews)
Designs for Health Liposomal Glutathione Spray is the only supplement on our list that is in spray form. This supplement is much smaller than the other ones and contains only 1.7 fl oz per bottle. Designs for Health recommends taking two pumps of the spray per dose for a total of 100mg of glutathione.
Even though this form is convenient and easy to take, the glutathione dosage is far from ideal. Studies suggest that a recommended intake to see results begin at 400mg per day. Additionally, this product also has the issue of oxidation. Unpleasant taste and smell become worse over time. Finally, at that price point it is one of the worst values per dollar.
100mg Glutathione
$50.25BUY NOW
+ Convenient Spray
+ Manufactured in the USA
–Low glutathione per dose
–Worst dollar value
5. Starhonor Liposomal Glutathione Softgels™
★★★★★ 4.5 (380 Reviews)
Starhonor Liposomal Glutathione Softgels™ is the only supplement in our list that is not presented in liquid form. Compared to liquid glutathione, softgels have a substantially lower chance of being absorbed by the body. We do not recommend this product for those seeking high glutathione absorption.
However, this supplement does include 1000mg of glutathione per dose, 300mg of vitamin c, and 50mg of Hyaluronic acid. It may provide some immune support over time and has a lower price point that other options. Again, we do not recommend this product compared to the other ones on the list. However, from all the non-liquid forms this is our most recommended.
1000mg Glutathione
400mg Liposomal blend
300mg Vitamin C
50mg Hyaluronic Acid
$39.99BUY NOW
+ Good immune support blend
+ Manufactured in the USA
– Low absorption compared to liquid glutathione
– Unlikely to see significant results
WHAT IS GLUTATHIONE
Glutathione is a nutrient-like compound that is one of the most versatile and important
protective substances in the human body. It is found to varying degrees in all tissues, body fluids, and organ systems, where it plays a variety of roles in health, including:
• elimination of cancer-causing chemicals
• antioxidant
• regeneration of vitamins C and E
• support the immune system
• maintenance of cellular proteins
• Protect cells from the action of very harmful compounds called free
radicals
Glutathione is a key player in the body’s antioxidant defenses. At a biochemical level, this means it can stop oxidative reactions by donating electrons to free radicals, much like other familiar antioxidants such as vitamin C, vitamin E, and many carotenoids. However, glutathione goes further: when
vitamins C and E are “spent” as antioxidants, they are regenerated by glutathione. Thus, glutathione not only acts directly to prevent oxidative damage to cells but also indirectly by supporting a powerful antioxidant team.
Another virtue of the glutathione molecule is its speed. When a cancer-causing chemical threatens to damage a cell’s DNA and cause a mutation, glutathione can react with the invader faster than the invader can react with DNA. In this way, glutathione intercepts and neutralizes many toxic substances.
These protective functions occur continually in all major organ systems, including the brain, heart, skeletal muscle, skin, and immune system, in addition to the liver, kidneys, intestines, and lungs.
BENEFITS OF GLUTATHIONE SUPPLEMENTS INCLUDE:
• Help maintain healthy immune function, contributing to the prevention of infectious
diseases.
• Boost energy, reduce fatigue, and support a healthy mitochondrial function, which
plays a key role in energy (ATP) production in cellular tissue.
• Help in the cellular detox process.
• Support cognitive improvement.
• Support muscle recovery by reducing oxidative stress, improving performance, and
fast recovery after physical exertion.
• Support joint health
• Help maintain healthy metabolic function, which supports restorative
sleep.
• Promote healthier, softer, and supple skin.
• Help maintain a healthy hormonal balance for women.
